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The objective of this paper is to present a new method for protecting the lives of residents in catastrophic earthquake failures of unreinforced masonry buildings by introducing some safe rooms within the buildings. The main idea is that occupants can seek refuge within the safe rooms as soon as the earthquake ground motions are felt. The information obtained from the historical ground motions happened in seismic zones around the globe expresses the lack of enough safety of masonry buildings against earthquake. For this potentially important reason, an attempt has been made to create some cost-effective seismic-resistant areas in some parts of the existing masonry buildings, which are called safe rooms. The practical method for creating these areas and increasing the occupant safety of the buildings is to install some prefabricated steel frames in some of their rooms or in their halls. These frames do not carry any service loads before earthquake. However, if a near field seismic event happens and the load bearing walls of the building destroy, some parts of its floors, which are in the safe areas, will fall on the roof of the installed frames consequently, the occupants who have sheltered in the safe rooms will survive. This paper expresses the experimental and theoretical work executed on the steel structures of the safe rooms for bearing the shock and impact loads. Finally, it was concluded that both the strength and displacement capacity of the steel frames were adequate to accommodate the distortions generated by seismic loads and aftershocks properly.