Sasan Khalifehzadeh, Mohammad Bagher Fakhrzad,
Volume 29, Issue 3 (9-2018)
Abstract
Abstract
Production and distribution network (PDN) planning in multi-stage status is commonly complex. These conditions cause significant amount of uncertainty relating to demand and lead time. In this study, we introduce a PDN to deliver the products to customers in the least time and optimize the total cost of the network, simultaneously. The proposed network is four stage PDN including suppliers, producers, potential entrepots, retailers and customers with multi time period horizon with allowable shortage. A mixed integer programming model with minimizing total cost of the system and minimizing total delivery lead time is designed. We present a novel heuristic method called selective firefly algorithm (SFA) in order to solve several sized especially real world instances. In SFA, each firefly recognizes all better fireflies with more brightness and analyses its brightness change before moving, tacitly. Then, the firefly that makes best change is selected and initial firefly moves toward the selected firefly. Finally, the performance of the proposed algorithm is examined with solving several sized instances. The results indicate the adequate performance of the proposed algorithm.
Mehdi Seifbarghy, Mehri Nasrabadi,
Volume 34, Issue 3 (9-2023)
Abstract
One of the most key parts of a health system is the blood supply chain whose design is challenging due to the perishability of blood. In this research, an optimization model for multi-product blood supply chain network design is presented by considering blood deterioration. We consider a four-echelon blood supply chain that consists of blood donation centers, blood processing centers, blood products storage centers and hospitals as the user of the blood products. The locations of blood processing centers and blood products storage centers should be determined. Furthermore, considering different levels of technologies for blood processing, the suitable level for each opened center should be determined. In addition, different types of vehicle are also considered for blood transfer between different levels of the network. The objective is minimizing the total logistical costs including the costs of opening and running the blood processing centers and blood product storage centers and blood products transfer costs between different levels of the supply chain. Finally, we apply the given model to a real case study in Iranian blood supply chain, and sensitivity analysis is performed on some parameters. In the end, some managerial insights are given
