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Montmorillonite modified as an efficient and environment friendly catalyst for one- pot synthesis of 3, 4-dihydropyrimidine-2(1H) ones
Dr Ali Darehkordi, Mr Mohammad Sadegh Hosseini,
Volume 9, Issue 3 (september 2012)
Abstract
Montmorillonite modified is an efficient environmental friendly catalyst under one-pot-three-component synthesis of 3,4-dihydropyrimidine-2(1H) ones. The preparation was performed with an aldehyde, 1,3-dicarbonyl compounds, urea or thiourea under solvent-free conditions. In comparison with the other methods of Biginelli reaction, this new method has short reaction time inexpensive catalyst and in addition excellent yields were obtained.
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